Sodium Monochloroacetate

Origin
India
CAS Number
3926-62-3
HS Code
29154000

Basic Info

IUPAC Name
sodium 2-chloroacetate
Molecular Formula
C2H2ClNaO2
Molecular Weight (g/mol)
116.4800
Synonyms & Trade Names
Sodium monochloroacetate; SMCA; Chloroacetic acid sodium salt
Purity / Assay (%)
98% min
Grade / Quality Level
Technical Grade
Physical Form
Solid
Concentration
Pure substance
Appearance / Color
White to off-white solid
Odor
Slight acetic
Melting Point (°C)
235.0000
Density (g/cm³)
1.7740
Solubility in Water
Freely soluble
Signal Word
Danger
UN Number
2659
GHS Hazard Class
Acute toxic; Skin corrosive; Eye corrosive
H-Statements
H302|H312|H314|H331
P-Statements
P260|P264|P271|P280|P301+P330+P331
REACH Status
Registered
Drug Precursor Status
Non-precursor
Storage Class (GHS)
6.1
Storage Conditions
Cool, dry; away from acids

Categories

Technical Document

Brief overview
Sodium Monochloroacetate is the sodium salt of chloroacetic acid. It is considered to be hygroscopic and thus must be handled with extreme care. It is a white-colored free-flowing fine powder with a slightly pungent odor. It is readily soluble in water.
Manufacturing Process
Sodium Monochloroacetate is an important industrial product, particularly for use as an intermediate reactant in the synthesis of many pharmaceutical and agrochemical products. Many processes have been developed to prepare sodium monochloroacetate, which are essentially based on the neutralization of monochloroacetic acid with bases such as sodium hydroxide and sodium carbonate. The process involves the neutralizing the molten monochloroacetic acid with concentrated caustic soda (50-55%), sodium carbonate in the form of a suspension or concentrated solution or in the form of a powder in a spray dryer. This process in which sodium carbonate is introduced together with hot air at 100 ℃ while molten monochloroacetic acid is sprayed at 80 ℃. In general, all these processes are carried out either under anhydrous conditions or with rapid removal of water (spray drying), which gives the sodium monochloroacetate in the form of a fine powder having a tendency to agglomerate and thus to flow poorly during pneumatic conveying or decantation.